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Dialyzer
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Diarenneedle Arterio Venous (A.V.) Blood Line
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Diadez PAA

Purifier High-Flux Dialyzer

Purifier H

PURIFIER H SYNTHETIC HIGH-FLUX DIALYSERS

A member of Purifier Family, proven clinical record, renowned biocompatibility,

The capillaries are made of Membrana's new technology PUREMA Polyethersulfone membranes. Clinical studiew proved outstanding performance of Purifer High-Flux Dialyzers thanks to its new technology Polyethersulfone membrane structure.

Info

HIGH-FLUX DIALYSIS

The term high-flux dialysis refers to a form of hemodialysis that was developed in recent years to improve the efficiency of dialysis. It has succeeded in both improving the quality of dialysis and in shortening dialysis times.

The essential element of high-flux dialysis is the use of dialyzers (artificial kidneys) that have larger pores for the removal both of uremic toxins and of fluid. Blood urea nitrogen (BUN) is measured and followed as a reflection of all the toxins that the kidney normally removes. With high-flux dialysis, BUN clearly is removed more quickly. But there is also now evidence that larger molecules may also play an important role in causing the uremic symptoms that are both annoying and dangerous to dialysis patients. Such molecules are too big to be removed by conventional dialysis, but are removed with high flux dialyzers. For example, a molecule called beta 2 microglobulin, which can have a role in causing arthritis in dialysis patients, is removed only by high-flux dialysis. In fact there are already reports of patients with less joint pain when switched from conventional to high-flux dialysis. Thus, the removal of larger molecules may prove to be a crucial benefit of high flux dialysis.

The larger pore size with high-flux dialysis also allows much faster removal of fluid. Because of the risk of removing fluid too fast, and causing dangerous drops in blood pressure, a special device, called an ultrafiltration controller, is required. This device allows precise regulation of the volume that is removed, and avoids ever overshooting the amount removed. It also allows the accurate removal of very small volumes, as well as volumes up to four liters per hour, which can never be achieved with conventional dialysis. Finally, since the fluid is removed continuously and evenly, removal of large volumes is better tolerated with fewer symptoms.

Another important aspect of high-flux dialysis is that higher blood and dialysate flows are used. With conventional dialysis, increasing the rate of blood flow (for example above 300 ml/min) minimally increases the amount of dialysis. In contrast, with high-flux dialyzers, when blood flow is increased up to 450 ml/min, significant improvements in dialysis efficiency can be obtained. Similarly, increasing the rate of dialysate flow allows faster removal of the toxins that are being cleared.

Nephrologists typically use some form of the technique called urea kinetic modeling to determine their dialysis prescription. Using national standards for adequacy of dialysis, and after taking residual renal function into account, urea kinetic modeling uses the dialyzer’s performance characteristics and the patient’s weight to derive an estimate of the time required for dialysis. Since high-flux dialysis (also called high efficiency dialysis in some centers) is so much more efficient, it can allow significant reduction of dialysis times, often by 25 percent. Thus, the patient receives adequate dialysis, but minimizes the discomfort of long dialysis times. However, it is important to note that adequacy of dialysis must be maintained. Some patients may not be able to greatly shorten dialysis times when switching from conventional to high flux dialysis.

Several other aspects of modern dialysis, including the use of bicarbonate dialysate, are an essential part of high-flux dialysis. However, they are now typically part of conventional dialysis as well. Bicarbonate is now routinely used as the dialysate buffer because the acetate that was used previously caused dilatation of blood vessels and resulted in low blood pressure. Another characteristic of high-flux dialysis is that the membranes used are more biocompatible, and therefore are less likely to stimulate the body’s immune system. This minimizes the allergic symptoms as well as the changes in white blood cell counts that were previously caused by less biocompatible membranes.

The major possible disadvantage of high flux dialysis regards pyrogen reactions. These reactions, characterized by high temperatures in patients during dialysis treatments, are caused by small pieces of dead bacteria that can be found in the dialysate. Although these reactions are not dangerous, they are uncomfortable for patients, and typically require short hospitalizations for observation. Some nephrologists feel that because high flux dialyzers have larger pores, the bacterial particles can pass more easily into the patient’s bloodstream, and that patients on high flux dialysis have more frequent pyrogen reactions. This observation remains to be confirmed.

Patients are not required to make any changes from their point of view in using high flux dialysis. Typically, they actually feel better, especially in terms of having less post-dialysis fatigue. High flux dialysis requires only minor technical adjustments in the dialyzing system, and will continue to be adopted by more and more dialysis centers.

Reference

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PRODUCT

FOR 1 PCS 80*120 cm EURO PALLET

GROSS WEIGHT

Dialysers

720 PCS

200 Kg

MANNER OF DELIVERY

QUANTITY OF PALLET CONTAINED

40 FOOT CONTAINER

23 PALLET (80*120 EURO)

20 FOOT CONTAINER

11 PALLET (80*120 EURO)

STANDART TRUCK

30 PALLET (80*120 EURO)


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Farmasol Product Family

Dialyzer
Dialyzer
(High-Flux | Low-Flux)
Bicarbonate Cartridge
Bicarbonate Cartridge
Bicarbonate Bag
Hemodialysis Concentrates & Solution
Hemodialysis Concentrates & Solutions
Hemodialysis Disinfectants
Hemodialysis Disinfectants
Diarenneedle Arterio Venous (A.V.) Blood Line
Diarenneedle Arterio Venous (A.V.)
Blood Line
Diareneedle Arterio Venous (A.V.) Fistula Needle Set
Diareneedle Arterio Venous (A.V.)
Fistula Needle Set
Diadez PAA
Diadez PAA
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Farmasol attended Arab Health 2014

Farmasol attended Arab Health 2014

Farmasol attended Arab Health 2014 organized between 27.01.2014 - 30.01.2014 in Dubai.more

Farmasol is a specialty pharmaceutical company developing and commercializing Hemodialysis products of highest quality to improve patients’ health. Farmasol believes there are significant business advantages to focusing on one singular area Our singular focus is to apply our expertise in Hemodialysis where we have proven expertise and where we believe we can have an even greater impact on patients. At Farmasol we are focused on exceptional performance because we know there are millions of patients waiting to benefit from our products and services. Since 2004 Farmasol has continually evolved to advance high quality products in hemodialysis —shaping high quality and cost effective solutions to help people lead healthier lives. Today, Farmasol is one of the far-reaching health care leaders in Turkey. Our expertise across Hemodialysis inspires innovations that address health needs of people throughout their lives— all focused on advancing innovations that provide better options and outcomes for people in their pursuit of healthy lives. Recognizing the critically importance of quality and safety of Hemodialysis products for our patients, aall our efforts are toward a single end: to preserve and improve patient health by consistently delivering high quality, safe and effective specialty hemodialysis products, because, we are well aware of the fact that our work impacts people’s lives. That's why we at Farmasol are committed to improve health and well-being at every stage of life. We strive to provide access to safe, effective and affordable consumables and related health care services to the people who need them. Our business strategy has two legs; to produce high quality, safe and cost effective products in our core hemodialysis area and to partner and collaborate with leading institutions and companies in an effort to speed our product candidates to market. FARMASOL Medical Products Ind. and Trd. Co., which were founded in a 2550 m2 covered area in Organized Industrial Region of Kayseri in 2005, began to produce bicarbonate hemodialysis solutions with the brand, DIASOL, and disinfectants with the brand, DIADEZ.Besides production of hemodialysis solutions, FARMASOL started to sell DICEA, a semisynthetic dialyzer, and XENIUM, a synthetics dialyzer, by a contract done with Eczacıbaşı-Baxter. FARMASOL has continually evolved to advance practices in medicine, science and technology, thus needed to increase the area required for production to 4350 m2 and constructed another 1800 m2 of covered area in 2007. It began to produce arterial venous set and fistula needle with brand, DIARENNEEDLE within “Class 10000 clean rooms” which was built inside these areas. Thus recognizing the crucial importance of extensive water purification, in his way to excellency, as assuring water quality is a center-specific item, FARMASOL brought a new standard to its production site on water purification. In 2008, Farmasol obtained Turkey distributorship of DWA company, which is a worldwide leading company on water purification in hemodialysis centers, In 2012, Farmasol began to produce its own high quality and wide range of FARMA Cart cartridge bicarbonates and FARMA BAG bag bicarbonates which provides flexibility and freedom while preparing the concentrate. Recently in the beginning of 2013, Farmasol contstructed an additional 2.150 m2 production plant for its high end dialyzers and announced its new and unique product – PURIFIER DİALYZERs (a wide range of Polyethersulfone high flux and low flux dialyzers produced in collaboration with our German Partner ALPHA PLAN) and are very exciting by its high quality.